Cross-Coupling of Mesylated Phenol Derivatives

Cross-Coupling of Mesylated Phenol Derivatives with Potassium Cyclopropyltrifluoroborate

C–O activation of mesylates by a palladium catalyst and subsequent cross-coupling with potassium cyclopropyltrifluoroborate have been achieved with high yield. Both electron-enriched and electron-deficient aryl mesylates are suitable electrophilic partners for the Suzuki–Miyaura reaction. The scope was successfully extended to heteroaryl mesylates with yields up to 94%.